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叶酸受体介导的抗肿瘤药物研究进展(6)

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叶酸受体介导的抗肿瘤药物研究进展

· 114 · 药学学报 Acta Pharmaceutica Sinica 2009, 44 (2): 109 114

immunopathology and molecular identification as a folate-binding protein [J]. Am J Pathol, 1993, 142: 557 567. [7]

Leamon CP, Reddy JA, Vlahov IR, et al. Synthesis and biological evaluation of EC140: a novel folate-targeted vinca alkaloid conjugate [J]. Bioconjug Chem, 2006, 17: 1226 1232. [8]

Leamon CP, Deprince RB, Hendren RW. Folate-mediated drug delivery: effect of alternative conjugation chemistry [J]. Drug Target, 1999, 7: 157 169. [9]

Leamon CP, Cooper SR, Hardee GE. Folate-liposome- mediated antisense oligodeoxynucleotide targeting to cancer cells: evaluation in vitro and in vivo [J]. Bioconjug Chem, 2003, 14: 738 747.

[10] Lomaestro BM, Malone M. Glutathione in health and disease:

pharmacotherapeutic issues [J]. Ann Pharmacother, 1995, 29: 1263 1273.

[11] Cordes EH, Jencks WP. The mechanism of hydrolysis of

Schiff bases derived from aliphatic amines [J]. J Am Chem Soc, 1963, 85: 2843 2848.

[12] Leamon CP, Reddy JA, Vlahov IR, et al. Synthesis and

biological evaluation of EC72: a new folate-targeted chemotherapeutic [J]. Bioconjug Chem, 2005, 16: 803 811. [13] Reddy JA, Westrick E, Leamon CP, et al. Folate receptor

specific anti-tumor activity of folate-mitomycin conjugates [J]. Cancer Chemother Pharmacol, 2006, 58: 229 236.

[14] Henne WA, Kularatne SA, Low PS, et al. Synthesis and

activity of a folate peptide camptothecin prodrug [J]. Bioorg Med Chem Lett, 2006, 16:5350 5355.

[15] Vlahov IR, Santhapuram HKR, Kleindl PJ, et al. Design and

region-selective synthesis of a new generation of targeted chemotherapeutics. Part 1: EC145, a folic acid conjugate of desacetylvinblastine monohydrazide [J]. Bioorg Med Chem Lett, 2006, 16: 5093 5096.

[16] Leamon CP, Reddy JA, Vlahov IR, et al. Comparative

preclinical activity of the folate-targeted vinca alkaloid conjugates EC140 and EC145 [J]. Int J Cancer, 2007, 121: 1585 1592.

[17] Leamon CP, Reddy JA, Vlahov IR, et al. Preclinical

antitumor activity of a novel folate-targeted dual drug conjugate [J]. Mol Pharm, 2007, 4: 659 697.

[18] Vlahov IR, Santhapuram HKR, Wang Y, et al. An assembly

concept for the consecutive introduction of unsymmetrical disulfide bonds: synthesis of a releasable multidrug conjugate of folic acid [J]. J Org Chem, 2007, 72: 5968 5972.

[19] Vite GD, Lee FY, Leamon CP. Conjugates of aziridinyl-

epothilone analogs and pharmaceutical compositions comprising same: US, 20070275904 [P]. 2007-11-29.

[20] Suzuki T, Hisakawa S, Itoh Y, et al. Design, synthesis, and

biological activity of folate receptor-targeted prodrugs of thiolate histone deacetylase inhibitors [J]. Bioorg Med Chem Lett, 2007, 17: 4208 4212.

[21] Schneider R, Schmitt F, Frochot C, et al. Design, synthesis,

and biological evaluation of folic acid targeted tetraphenylporphyrin as novel hotosensitizers for selective photodynamic therapy [J]. Bioorg Med Chem, 2005, 13: 2799 2808.

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