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Acknowledgements

TheauthorsacknowledgesupportforthisworkfromNSFC(grantnos20672006,

20821062,GZ419)andthe‘973’ProjectfromtheMOSTofChina(2009CB825300).TheauthorsalsothankJ.ZhangatEastChinaNormalUniversityandN.JiaoattheMedicalSchoolofPekingUniversityandtheirstudentsforrepeatingourexperiments.The

polishingoftheEnglishandtheconstructivecommentsfromK.ItamiatNagoyaUniversityandC.HefromtheUniversityofChicagoaregreatlyappreciated.

Authorcontributions

Z.-J.S.conceivedtheproject.C.-L.S.,H.L.andD.-G.Y.performedtheexperimentsandanalysedthedataandcontributedequallytothiswork.M.Y.,X.Z.,X.-Y.L.,K.H.andS.-F.Z.workedonproductisolationandpuri cation.C.-L.S.,B.-J.L.andZ.-J.S.wrotethepaper.C.-L.S.wrotetheSupplementaryInformationandcontributedotherrelatedmaterials.

Additionalinformation

Theauthorsdeclarenocompeting http://www.77cn.com.cn/

naturechemistry.Reprintsandpermissioninformationisavailableonlineathttp://www.77cn.com.cn/reprintsandpermissions/.CorrespondenceandrequestsformaterialsshouldbeaddressedtoZ.-J.S.

6NATURECHEMISTRY|ADVANCEONLINEPUBLICATION|http://www.77cn.com.cn/naturechemistry

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